Xylometazoline, like other sympathomimetic agents, should be used with caution in patients showing a strong reaction to adrenergic substances, as manifested by signs of insomnia, dizziness, tremors, cardiac arrhythmia, or elevated blood pressure.
Otrivin should be used with caution in patients with: hypertension, cardiovascular disease, hyperthyroidism, diabetes mellitus, phaeochromocytoma, prostatic hypertrophy, monoamine oxidase inhibitors (MAOI) treatment, or who have received them in the last two weeks.
As with other topical vasoconstrictors, Otrivin 0.1% should not be used for more than ten consecutive days: prolonged or excessive use may cause rebound congestion and/or atrophy of the nasal mucosa.3
Keep out of sight and reach of children.
Common side effects, with an incidence of approximately 10%, include dryness or irritation of the nasal mucosa, nausea, headache, or a local burning sensation.3 Occurring at a much lower incidence of approximate 0.0001%, are allergic reactions, including difficulty breathing or swallowing, swelling of the face, lips, tongue or throat, blurred vision, and irregular heartbeat.3
Do not use OTRIVIN ADULT Metered- Dose Nasal Spray before talking to your doctor or pharmacist if any of the below apply:3
- you have high blood pressure
- you suffer from heart disease
- you have an overactive thyroid gland (hyperthyroidism)
- you suffer from diabetes
- you have an enlarged prostate gland (prostatic hypertrophy)
- you have a rare tumour of the adrenal gland that produces high amounts of adrenaline and noradrenaline (phaeochromocytoma)
- you are taking certain medicines used for the treatment of depression. These medicines are: -Monoamine oxidase inhibitors (MAOI): do NOT use (X) if you are taking or have been taking MAOIs within the last 14 days -tri-cyclic and tetra-cyclic antidepressants
As with other products for the relief of a blocked nose, OTRIVIN ADULT Metered- Dose Nasal Spray may give rise to sleep disturbances, dizziness, or tremors in very sensitive patients. Consult your doctor if such signs prove troublesome.3