Excedrin^® Overview

Excedrin^® Overview

Help your patients find headache and migraine relief fast with Excedrin, a leader in headache relief for over 50 years.

Recommend Excedrin^® Migraine as first-line therapy in the treatment of migraine¹

First-line Therapy

Recommend Excedrin^® Migraine as first-line therapy in the treatment of migraine.¹ It’s the #1 Neurologist Recommended OTC.^*

Woman with a migraine massaging her head

Powerful Analgesic

Excedrin^® Migraine targets key symptoms of migraine with or without aura.²

Icon displaying effective migraine relief with just 1 dose

One-Dose Relief

In clinical studies, patients with moderate to severe migraines experienced effective relief with just one dose.

More About Excedrin^® Migraine
Similar to 1 Cup of Coffee

Excedrin^® Migraine contains a level of caffeine similar to the amount in 1 cup of coffee. Without caffeine, a 40% higher analgesic dose is necessary to achieve the same level of pain relief.³

Starts Relieving Migraine Pain in 30 Minutes for Some Patients²

Excedrin^® Migraine significantly reduces pain and migraine-associated symptoms such as²:

Nausea

Photophobia

Phonophobia

Proven Safety Profile

Doctor-recommended and effective OTC migraine treatment with a proven safety profile

Graph of triple action: acetaminophen, aspirin, caffeine

Triple-Action Formula

Excedrin^® Migraine combines aspirin, acetaminophen, and caffeine

Discover Excedrin^®for Headaches and Migraines

Excedrin^® Extra Strength Fast-Acting Formula

For some, headache relief starts in as little as 15 minutes.⁴

Excedrin^® Migraine

The #1 neurologist-recommended OTC treatment for migraines^*

Understanding Headaches & Migraines

What Are Headaches & Migraines?

Find out more about how headaches and migraines impact people’s lives.

Learn more

What Causes Headaches & Migraines?

Discover the causes and triggers for headaches and migraines.

Learn more

How Can Patients Manage Headaches & Migraines?

Learn about different management options for headaches and migraines.

Learn more

Patient FSA / HSA Eligible Product

This product is eligible for Flexible Spending Account (FSA) and Health Savings Accounts (HSA)

Resulting from the CARES Act recently passed by congress, you can now use your FSA and HSA tax-preferred savings account to purchase certain OTC products such as Flonase, Nicorette, Nicoderm, Advil, Voltaren, and Denture Care Products. Your plan details may vary, so make sure to save your receipt and check with your benefits or health provider for eligibility. Please visit our page on Using My FSA/HSA.

Footnotes:

*Among OTC medicines for migraines. IQVIA 2018.

References

Silberstein SD, Armellino JJ, Hoffman HD, et al. Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies. Clin Ther. 1999;21(3):475-491.
Lipton RB, Stewart WF, Ryan RE Jr, Saper J, Silberstein S, Sheftell F. Efficacy and safety of acetaminophen, aspirin, and caffeine in alleviating migraine headache pain: three double-blind, randomized, placebo-controlled trials. Arch Neurol. 1998;55(2):210-217.
Laska EM, Sunshine A, Mueller F, Elvers WB, Siegel C, Rubin A. Caffeine as an analgesic adjuvant. JAMA. 1984;251(13):1711-1718.
Data on file. Study 133-01-99. Novartis Inc.

This site is intended for US healthcare professionals only.

PM-US-XCDRN-21-00145

Excedrin® Overview