Children’s Advil
![Children’s Advil ibuprofen 100-mg fever reducer and pain reliever in grape-flavored liquid](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ps-advil-aide-us-children-970x416.png?auto=format)
Safe for children. Approved by parents.
Children’s Advil has an excellent safety profile when used as directed.1-4
![Masked doctor talks with young patient](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ls-advil-aide-us-children-safety_970x416-copy.png?auto=format)
Children’s Advil has an excellent safety profile when used as directed1-4
A meta-analysis of 24 randomized clinical trials in pediatric subjects concluded that ibuprofen has a proven tolerability and safety profile comparable to placebo in terms of gastrointestinal symptoms, asthma, and renal adverse events.2
In a large, randomized, double-blind trial, it was shown that in short-term use of ibuprofen in children, there was a low risk of hospitalization for renal failure, gastrointestinal bleeding, or anaphylaxis (N=84,192).5
The follow-up period of an actual-use trial that included nearly 25,000 pediatric patients (approximately 13,800 of whom received ibuprofen) showed that less than 1% of pediatric patients treated with Children’s Advil experienced any of the most frequently reported adverse events identified in the trial, which are listed in the table below.4
This trial was a national, multicenter, observational study conducted in a naturalistic outpatient pediatric setting to evaluate the experience with Children’s Advil in children with fever and pain.4
![Chart showing potential adverse events and the percentage of patients who experience them after taking Children’s Advil](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ig-advil-aide-us-children-ibp-adverse_970x416.png?auto=format)
Common adverse events in pediatric patients taking ibuprofen4
Children’s Advil has a wide margin of safety and a low potential for toxicity from overdose as demonstrated in several studies.6,7
![Father lying on the ground lifts his son in the air](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ls-advil-aide-us-children-boyplaying_970x416.png?auto=format)
Children’s Advil brings fever down faster and keeps it down longer than Children’s Tylenol4,8*†
Nothing reduces fever faster* or keeps it down longer than Children’s Advil®—up to 8 hours of fever relief and nothing has been proven better on fever, not even Children’s Motrin®.4,9*†
Additionally, Children’s Advil provides more effective fever control with less frequent dosing (every 6-8 hours) than Children’s Tylenol® (as labeled, every 4 hours).4,8
Studies demonstrated that in pediatric patients, ibuprofen provided faster and longer fever reduction than acetaminophen.4,8*
*Based on reducing fever below 100°F.†Among leading OTC pain relievers/fever reducers.
![Graph showing results from a study on fever reduction after taking Children’s Advil](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ig-advil-aide-us-children-temperature-chart-970x416.png?auto=format)
Fever reduction with Children’s Advil vs Children’s Tylenol4
Efficacy results from a double-blind, single-dose, parallel-group study comparing the antipyretic efficacy and safety of ibuprofen pediatric suspension and acetaminophen in children with fever (N=160).4
Statistically fewer treatment failures with ibuprofen vs acetaminophen at 4 and 6 hours after initial dose.4‡
‡Treatment failure was defined as an increase in temperature of 1°F above the baseline temperature or an absolute temperature of greater than 104.9°F rectally or 103.9°F orally at any time during the postdosing follow-up period, or if there was no evidence of drug effect any time after the 2-hour postdosing time point.
![Infants’ Advil ibuprofen 50-mg, dye-free fever reducer and pain reliver in white grape–flavored drops](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ps-advil-aide-us-infants-970x416.png?auto=format)
Infants’ Advil—gentle infants’ fever relief
Infants’ Advil delivers unsurpassed fever relief* that baby can stomach.9,10†
- Nothing works faster9*
- Nothing keeps fever down longer9†
- Gentle on baby’s stomach10
*Based on reducing fever below 100°F.†Among leading over-the-counter pain relievers/fever reducers.
![Masked doctor greets young child](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ls-advil-aide-us-children-infant-children_970x416.png?auto=format)
Children’s Advil is indicated for children aged 2-11 years and Infants’ Advil is indicated for infants 12 pounds to 23 pounds and 6 months through 23 months of age. Please refer to Children’s Advil and Infants’ Advil Drug Facts for full product information.
Recommend Children’s and Infants’ Advil
![Children’s and Infants’ Advil fever reducer and pain reliever](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/pain-relief/advil/childrens-advil/ps-advil-aide-us-children-infants_750x421.png?auto=format)
Recommend Children’s and Infants’ Advil
Children’s and Infants’ Advil have a trusted safety profile with superior fever relief.
Learn more about Children’s and Infants’ Advil
![Drawing of pill and magnifying glass](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/icons/GSK_GEP_conditions_icon_750x421.png?auto=format)
Children’s Advil Drug Facts
The drug facts contain all you need to know about Children’s Advil, as well as nonsteroidal anti-inflammatory drug (NSAID) and acetaminophen warnings.
![Drawing of pill and magnifying glass](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/icons/GSK_GEP_conditions_icon_750x421.png?auto=format)
Infants’ Advil Drug Facts
The drug facts contain all you need to know about Infants’ Advil, as well as NSAID and acetaminophen warnings.
![Drawing of family](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_US/icons/GSK_GEP_Patient_Resources_Icon.png?auto=format)