Comparing the Safety Profile of Ibuprofen at OTC and Prescription Doses

Summary
Ibuprofen is generally well tolerated at recommended OTC doses (up to 1200 mg/day) for up to 7–10 days; however, caution is always advised particularly with higher doses and extended use to minimize the risk of GI and CV complications.
Read this study summary assessing the safety profile of ibuprofen when taken at OTC doses versus prescription doses.