Voltral Science - Diclofenac
Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source
Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,
![Relative potency of diclofenac, ketoprofen and ibuprofen](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/pain-relief/voltaren/GSK_Voltaren%20corevisuals_final_970x416%20.jpg?auto=format)
Diclofenac is a potent anti-inflammatory agent1
Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2
Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.4
Diclofenac targets inflammation to strike pain at its source
Diclofenac-containing products
![Voltral Triple Effect 1.16% Emulgel](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/pain-relief/packshots/Voltral_1%25PS.jpg?auto=format)
Voltral Triple Effect 1.16% Emulgel
For patients who are looking for relief from sprains and strains, using a topical formulation.
![Voltral 12-hour 2.32% Emulgel](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/pain-relief/packshots/Voltral_2%25PS.jpg?auto=format)
Voltral 12-hour 2.32% Emulgel
For patients who are looking for long-lasting relief from joint pain and inflammation, using a topical formulation.
Diclofenac – a potent anti-inflammatory ingredient1
![Diclofenac-containing products](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/pain-relief/packshots/Voltral_FamilyPS.png?auto=format)
Diclofenac-containing products
Learn more about Voltral products that contain this potent anti-inflammatory ingredient.1
![Patient care resources](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/icons/GSK_GEP_patient_care_resources_orange.png?auto=format)
Patient care resources
Review educational materials on Voltral products for your patients.
![Educational resources](https://i-cf65.ch-static.com/content/dam/cf-consumer-healthcare/health-professionals/en_PK/icons/GSK_GEP_Educate_Icon.png?auto=format)