Voltral Science - Diclofenac

Acts through cyclo-oxygenase-2 (COX-2) inhibition, striking inflammation at its source

Learn how diclofenac reduces inflammation by inhibiting prostaglandin biosynthesis through action on the COX enzymes with selectivity for COX-2, and inhibiting phospholipase A2 activity to reduce the production of inflammatory leukotrienes.1,2,

Relative potency of diclofenac, ketoprofen and ibuprofen

Diclofenac is a potent anti-inflammatory agent1

Its effect on the COX-2 enzyme means that, unlike non-NSAID medications such as paracetamol, diclofenac not only provides pain relief but also treats inflammation – a root cause of pain.2

Diclofenac, an NSAID (and therefore in the same drug class as ketoprofen and ibuprofen), shows marked potency in its inhibition of the COX-2 enzyme.4

Diclofenac targets inflammation to strike pain at its source

Diclofenac-containing products

Voltral Triple Effect 1.16% Emulgel

Voltral Triple Effect 1.16% Emulgel

For patients who are looking for relief from sprains and strains, using a topical formulation.

Voltral 12-hour 2.32% Emulgel

Voltral 12-hour 2.32% Emulgel

For patients who are looking for long-lasting relief from joint pain and inflammation, using a topical formulation.

Diclofenac – a potent anti-inflammatory ingredient1

Diclofenac-containing products

Diclofenac-containing products

Learn more about Voltral products that contain this potent anti-inflammatory ingredient.1

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Patient care resources

Patient care resources

Review educational materials on Voltral products for your patients.

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Educational resources

Educational resources

Access detailed clinical information about diclofenac.

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