Nexium Control formulation

How Nexium Control works

View the video to learn more about the mode of action of Nexium Control.

Image of stomach with acid before and after treatment

The science of Nexium Control

Acid reflux, a cause of heartburn, occurs when the lower oesophageal sphincter relaxes, allowing excess stomach acid (HCl) to enter the oesophagus.1 Stomach acid is formed by the binding of hydrogen (H+) and chloride (Cl-) ions produced by the gastric parietal cells lining the stomach.1 Nexium Control works by irreversibly binding to the enzyme proton pump that allows the gastric parietal cells to secrete H+ ions, preventing it from working.2 This can start to work in 1 hour,* and reduces the production of stomach acid for up to 24 hours to provide long-lasting heartburn relief.

*Full effect may take 2-3 days

Unlike short-acting relief, Nexium Control works to provide up to 24 hours of continuous relief from frequent heartburn

Do more than just treat the burning pain of heartburn, tackle it at its source.

Image of short term action of antacids

Antacids and alginates may only provide short acting relief

Antacids react with gastric acid, neutralising it.3

Alginates form a temporary physical barrier (or raft) on top of the stomach helping to prevent the contents from escaping through the sphincter.4 Their effectiveness depends on the stomach contents, with them being less effective if taken during a meal or when lying down.4

For both antacids and alginates, once the stomach empties, their effects cease. Repeated dosing is necessary to provide relief from newly secreted acid.5,6

This need for repeat dosing can lead to patients developing a ‘burn-suffer-treat' reactive cycle which may not provide the sustained relief from frequent heartburn that they need.

Image of Nexium Control breaking the cycle of heartburn

Nexium Control provides long-lasting relief

Nexium Control, with esomeprazole, reduces the production of stomach acid for up to 24-hour protection, treating the cause and symptoms of heartburn and allowing time for the oesophagus to recover from the acid irritation.

Protection is achieved with the convenience of once-a-day dosing*.

*Some people experience relief within a day, though for some, it may take 2 – 3 days for complete relief.

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Nexium Control tablets pack

Nexium Control 20mg Gastro-Resistant Tablets (Esomeprazole)

Nexium Control 7 tablet pack is an ideal trial pack with one-week supply. Nexium Control 14 tablet pack offers the same protection and offers a 2-week treatment course.

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Nexium Control tablets pack

Nexium Control 28 tablet pack

Offers value and convenience for patients with frequent heartburn who have used esomeprazole successfully before.

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Nexium Control Capsules pack

Nexium Control 20mg Gastro-Resistant Capsules (Esomeprazole)

Easy-to swallow mini capsules. Complete 14-day treatment course.

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  • Product Information

    Product Information: Please consult the Summary of Product Characteristics for full product information. Nexium Control 20 mg gastro-resistant tablets and Nexium Control 20 mg gastro-resistant hard capsules (esomeprazole). Indications: The short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Dosage: One tablet or capsule per day. May need to be taken for 2-3 consecutive days to achieve symptom improvement. Maximum treatment duration: up to 2 weeks. Contraindications: Hypersensitivity to the active substance, substituted benzimidazoles or to any of the excipients. Esomeprazole must not be used concomitantly with nelfinavir. Precautions: Refer to doctor if patient has: Jaundice or severe liver disease, significant unintentional weight loss, recurrent vomiting, dysphagia, haematemesis or melaena and when gastric ulcer is suspected or present, malignancy should be excluded as treatment with esomeprazole may alleviate symptoms and delay diagnosis, previous gastric ulcer or gastrointestinal surgery, continuous treatment of indigestion or heartburn for 4 or more weeks, or is over 55 years old with new or recently changed symptoms. Not suitable for long term use. May lead to a slightly increased risk of gastrointestinal infections e.g. Salmonella and Campylobacter and in hospitalised patients, possibly Clostridium difficile. Consult doctor prior to having an endoscopy or urea breath test. Co-administration with atazanavir is not recommended. Interactions with medicinal products metabolised through CYP2C19 should be considered. The use of esomeprazole with clopidogrel should be discouraged. Do not take another PPI or H2 antagonist concomitantly. Increased Chromogranin A (CgA) can interfere with neuroendocrine tumour investigations. Stop Nexium Control at least 5 days before CgA measurements. Very infrequent cases of SCLE may occur. If lesions occur, especially in sun-exposed areas of the skin, and if accompanied by arthralgia, the patient should seek medical help promptly. Healthcare professional should consider stopping treatment. Contain sucrose, patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product. Capsules only: Contain Allura red AC (E129) which can cause allergic reactions. Side effects: Common: headache, abdominal pain, constipation, diarrhoea, flatulence, nausea/ vomiting, fundic gland polyps (benign). For uncommon, rare, very rare and other side effects please refer to the SPC for full information. Legal category: Supply through pharmacy only. Product licence number: Tablets: EU/1/13/860/001; EU/1/13/860/002; EU/1/13/860/004. Capsules: EU/1/13/860/003; and EU/1/13/860/005. MAH: GlaxoSmithKline Dungarvan Limited, Knockbrack, Dungarvan, County Waterford, Ireland. Additional information is available upon request. Text prepared: June 2024.

    Contains esomeprazole. Always read the label/leaflet.

Nexium Control – For up to 24-hour heartburn relief with just one pill

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Educational Resources

Access educational resources to support your team’s understanding of heartburn and its management.

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Overview of frequent heartburn

Find out more about frequent heartburn including a profile of a patient who may suffer from the condition.

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