Nexium Control overview

Give your patients up to 24-hour heartburn relief - gets to work in 1 hour*

Unlike antacids and alginates that treat the symptoms of heartburn, Nexium Control tackles the cause by targeting acid directly at the source providing long-lasting protection.

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*Full effect may take 2-3 days

Nexium Control – Scientifically proven to provide up to 24 hours of protection from heartburn

Long lasting protection

With just one pill a day Nexium Control provides up to 24-hour protection for frequent heartburn sufferers.

Help return life to normal within 2 weeks

8 out of 10 people reported first resolution within the first week of treatment with Nexium Control.

Visual for 4 out of 5 nights heartburn free

Clinically proven night-time relief

4 out of 5 nights were heartburn free for patients using Nexium Control.

Nexium Control – Your first line recommendation for frequent heartburn

Frequency is key

A key question for heartburn sufferers

Suffering more than once per week with heartburn is classed as frequent heartburn.¹

Regardless of its severity, frequent heartburn makes the oesophagus sensitive to acid such that it does not take a lot to trigger burning pain.²

Ask your patients ‘How often do you suffer from heartburn each week?’

Learn more about how the frequency of heartburn may impact treatment recommendations by clicking here.

Up to 24-hour heartburn protection

Break the cycle of short-acting heartburn relief with Nexium Control

Nexium Control is a proton pump inhibitor (PPI) containing 20mg esomeprazole.

It works by reducing the production of acid in the stomach, providing up to 24-hour protection from heartburn.

Antacids and alginates only offer short-acting relief from the pain of occasional heartburn until the stomach empties. At this point more acid is produced and the cycle starts again.^3,4

Nexium Control can break the cycle of short-acting relief by reducing the production of stomach acid for up to 24 hours. It treats the cause and symptoms of heartburn, allowing time for the oesophagus to recover from the acid irritation.

	Duration of treatment	Mode of action
Antacids	1-3 hours⁴	Neutralises acid content in stomach. Repeated dosing necessary for newly secreted acid.^4,5
Alginates	Up to 4 hours³	Forms a raft on top of stomach contents to prevent escape through sphincter. Repeated dosing necessary for newly secreted acid.⁶
PPI’s e.g. esomeprazole	Up to 24 hours⁷	Acts on proton pump to reduce acid production. The lack of acid leaking from the stomach gives the oesophagus a ‘holiday’ from acid.⁷

Find out more about the science behind Nexium control

Helping to restore quality of life for sufferers
Nexium Control helps restore frequent heartburn sufferers’ quality of life

Frequent heartburn can cause significant disruption to people’s lives, forcing them to avoid certain foods or making it difficult to get a good night’s sleep.¹

Research has shown that within just 2 weeks of treatment with esomeprazole, the active ingredient in Nexium Control, the impact on quality of life by heartburn can be significantly reduced or normalised.

Improvements in scores were observed in nearly every quality-of-life parameter measured, including:⁸

Social functioning

Vitality

Activities affected by emotional or physical health

Pain
First line treatment for frequent heartburn

NICE guidelines recommend PPI’s, such as Nexium Control, as first line treatment for frequent heartburn⁹

Find out more about frequent heartburn

Explore videos, product guides and other resources to support you and your team when recommending Nexium Control for frequent heartburn.

Click here

Recommend Nexium Control for your patients with frequent heartburn

Nexium Control 28 tablet pack

For patients with recurrent frequent heartburn who have used esomeprazole successfully and seek the value and convenience of a larger pack.

For patients who have difficulty in swallowing, the tablets can also be dispersed in half a glass of non-carbonated water. No other liquids should be used as the enteric coating may be dissolved. Stir until the tablets disintegrate and drink the liquid with the pellets immediately or within 30 minutes. Rinse the glass with half a glass of water and drink. The pellets must not be chewed or crushed.

Nexium Control 20mg Gastro-Resistant Tablets (Esomeprazole)

Nexium Control 7 tablet pack is an ideal trial pack with one-week supply. Nexium Control 14 tablet pack offers the same protection and offers a 2-week treatment course.

For patients who have difficulty in swallowing the tablets can also be dispersed in half a glass of non-carbonated water. No other liquids should be used as the enteric coating may be dissolved. Stir until the tablets disintegrate and drink the liquid with the pellets immediately or within 30 minutes. Rinse the glass with half a glass of water and drink. The pellets must not be chewed or crushed.

Nexium Control 20mg Gastro-Resistant Capsules (Esomeprazole)

Easy-to swallow mini capsules – Complete 14-day treatment course.

*based on volume

Product Information

Product Information: Please consult the Summary of Product Characteristics for full product information. Nexium Control 20 mg gastro-resistant tablets and Nexium Control 20 mg gastro-resistant hard capsules (esomeprazole). Indications: The short-term treatment of reflux symptoms (e.g. heartburn and acid regurgitation) in adults. Dosage: One tablet or capsule per day. May need to be taken for 2-3 consecutive days to achieve symptom improvement. Maximum treatment duration: up to 2 weeks. Contraindications: Hypersensitivity to the active substance, substituted benzimidazoles or to any of the excipients. Esomeprazole must not be used concomitantly with nelfinavir. Precautions: Refer to doctor if patient has: Jaundice or severe liver disease, significant unintentional weight loss, recurrent vomiting, dysphagia, haematemesis or melaena and when gastric ulcer is suspected or present, malignancy should be excluded as treatment with esomeprazole may alleviate symptoms and delay diagnosis, previous gastric ulcer or gastrointestinal surgery, continuous treatment of indigestion or heartburn for 4 or more weeks, or is over 55 years old with new or recently changed symptoms. Not suitable for long term use. May lead to a slightly increased risk of gastrointestinal infections e.g. Salmonella and Campylobacter and in hospitalised patients, possibly Clostridium difficile. Consult doctor prior to having an endoscopy or urea breath test. Co-administration with atazanavir is not recommended. Interactions with medicinal products metabolised through CYP2C19 should be considered. The use of esomeprazole with clopidogrel should be discouraged. Do not take another PPI or H2 antagonist concomitantly. Increased Chromogranin A (CgA) can interfere with neuroendocrine tumour investigations. Stop Nexium Control at least 5 days before CgA measurements. Very infrequent cases of SCLE may occur. If lesions occur, especially in sun-exposed areas of the skin, and if accompanied by arthralgia, the patient should seek medical help promptly. Healthcare professional should consider stopping treatment. Contain sucrose, patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product. Capsules only: Contain Allura red AC (E129) which can cause allergic reactions. Side effects: Common: headache, abdominal pain, constipation, diarrhoea, flatulence, nausea/ vomiting, fundic gland polyps (benign). For uncommon, rare, very rare and other side effects please refer to the SPC for full information. Legal category: Supply through pharmacy only. Product licence number: Tablets: EU/1/13/860/001; EU/1/13/860/002; EU/1/13/860/004. Capsules: EU/1/13/860/003; and EU/1/13/860/005. MAH: GlaxoSmithKline Dungarvan Limited, Knockbrack, Dungarvan, County Waterford, Ireland. Additional information is available upon request. Text prepared: June 2024.

Contains esomeprazole. Always read the label/leaflet.

Ireland’s No 1 pharmacy only 24 hour heartburn protection treatment¹

Overview of frequent heartburn

Find out more about frequent heartburn including a profile of a patient who may suffer from the condition.

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Causes, triggers and impact

Find out more about the causes and triggers for frequent heartburn and the impact it has on your patients’ quality of life.