Haleon Day Nurse 500 mg / 30 mg Film-Coated Tablets (paracetamol, pseudoephedrine hydrochloride).
Indications: Symptomatic relief of nasal congestion when combined with fever and/or pain such as, sore throat, sinus pain or headache in the common cold or influenza.
Dosage and administration: The tablets should be taken with water. Minimum interval 4 hours between doses. Max 3 doses per 24 hours. Adults, incl. elderly: Two tablets up to three times daily as required. Adolescents 16-18 years old: One to two tablets up to three times daily as required. Adolescents 12-15 years old: One tablet up to three times daily as required. Do not use for more than 5 days.
Contraindications: Hypersensitivity to paracetamol, pseudoephedrine or any of the excipients. Use by patients taking other sympathomimetics (such as decongestants, tricyclic antidepressants, appetite suppressants and amphetamine-like psychostimulants), beta-blockers, moclobemide or monoamine oxidase inhibitors (MAOIs) or for two weeks after stopping the MAOI drug. Use with oxazolidinone class of antibiotics (including furazolidone and linezolid) or by patients with the following conditions: Hypertension, Cardiovascular disease, Hyperthyroidism, Prostatic hypertrophy, Glaucoma, Severe renal impairment (GFR<30mL/min). Use by children under 12 years of age.
Warnings and Precautions: Do not use with any other paracetamol-containing products and avoid use with other cold and flu medicines. Use with caution in patients over 60 years old, those with hepatic impairment or mild to moderate renal impairment, glutathione depletion due to metabolic deficiencies, psychosis, diabetes mellitus, arrhythmias or phaeochromocytoma, and in patients taking antihypertensives or vasoconstrictive agents such as ergot alkaloids. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. There have been reports of ischaemic colitis with pseudoephedrine, discontinue immediately if symptoms develop. Rare cases of posterior reversible encephalopathy (PRES) /reversible cerebral vasoconstriction syndrome (RCVS) reported with sympathomimetic drugs, discontinue immediately if symptoms develop. Severe skin reactions such as acute generalized exanthematous pustulosis (AGEP) may occur. Monitor patients, if symptoms such as pyrexia, erythema, or many small pustules occur, discontinue and take appropriate measures. Cases of ischaemic optic neuropathy have been reported, discontinue if sudden loss of vision or decreased visual acuity occurs. Use with care in patients undergoing general anaesthesia, due to risk of acute perioperative hypertension when used with volatile halogenated anaesthetics. Stop 24 hours before anesthesia. may result in a positive reaction during antidoping control tests. Caution is advised if paracetamol is administered concomitantly with flucloxacillin due to increased risk of high anion gap metabolic acidosis. Risk of hepatotoxicity with paracetamol doses in therapeutic range when one or more risk factor also present (see SPC for list). Use with caution with drugs that induce hepatic enzymes and in conditions which may predispose to glutathione deficiency.
Side effects: Please refer to the SPC for full details. Common: Nervousness, insomnia, dizziness, drymouth, nausea, vomiting.
Legal category and RRP (excl. VAT): P: £7.08
Product licence number: PL 15545/0011.
Product licence holder: Haleon Ireland Dungarvan Limited, Knockbrack, Dungarvan, County Waterford, Ireland.
Text prepared: December 2024.
